This purpose of this contribution is to present the distinctive features of two of the most important clinical–social approaches that follow from the systemic paradigm: the "intersubjective–narrative" approach, focused on principles and intervention modalities, and the "relational–generational" approach. Although originating from the same paradigm, each approach presents a history of research intervention and internal changes that should be recognized and appreciated as constituting two ­distinct approaches of thought and clinical intervention.