Since its inception in 1979, mindfulness-based stress reduction Mindfulness-Based Stress Reduction (MBSR) has been introduced into many community and institutional settings with a variety of populations. There is an understood caveat that the participants are able to understand and follow instructions, have a good attention span, are able to commit to the experience, and to participate in some form of exercise. In this chapter, I discuss group and individual interventions offered to populations who often are not able to meet the above criteria.