A non-monotonic logic, the Logic of Plausible Reasoning (LPR), capable of coping with the demands of what we call complex reasoning, is introduced. It is argued that creative complex reasoning is the way of reasoning required in many instances of scientific thought, professional practice and common life decision taking. For managing the simultaneous consideration of multiple scenarios inherent in these activities, two new modalities, weak and strong plausibility, are introduced as part of the Logic of Plausible Deduction (LPD), a deductive logic specially designed to serve as the monotonic support for LPR. Axiomatics and semantics for LPD, together with a completeness proof, are provided. Once LPD has been given, LPR may be defined via a concept of extension over LPD. Although the construction of LPR extensions is first presented in standard style, for the sake of comparison with existing non-monotonic formalisms, alternative more elegant and intuitive ways for constructing non-monotonic LPR extensions are also given and proofs of their equivalence are presented.