As information and communication technologies (ICTs) become an integral part of the tourism environments, tourism technologies are designed to generate impacts on tourists' behavior and transform tourism experiences. Drawing from behaviorism, philosophy of computing, design science and persuasive technology, this chapter provides a theoretical reflection for technology and tourism design by theorizing behavioral design and technological mediation in tourism experiences. It also provides guiding principles to bridge the theories into design practices in for tourism destinations to solve design problems by facilitating behavior change through ICTs. The ultimate goal is for tourism destinations to offer meaningful and memorable tourism experiences for tourists that are advantageous for all stakeholders.